NORRE Study
Модератор: Pyankov Vasily
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NORRE Study
Normal Reference Ranges for Echocardiography: rationale, study design, and methodology (NORRE Study)
Background
Availability of normative reference values for cardiac chamber dimensions, volumes, mass, and function is a prerequisite for the accurate application of echocardiography for both clinical and research purposes. However, due to the lack of consistency in current echocardiographic ‘reference values’, their use for clinical decision-making remains questionable.
Aims
The aim of the ‘Normal Reference Ranges for Echocardiography Study (NORRE Study)’ is to obtain a set of ‘normal values’ for cardiac chamber geometry and function in a large cohort of healthy Caucasian individuals aged over a wide range of ages (25–75 years) using both conventional and advanced echocardiographic techniques.
Methods
The NORRE Study is a large prospective, observational multicentre study in which transthoracic echocardiographic studies will be acquired in 22 laboratories accredited by the European Association of Cardiovascular Imaging and in one laboratory in the USA accredited by ICAEL. The final sample size has been estimated in 1100 normal subjects in whom M-mode, 2D, and 3D imaging, colour Doppler, pulsed-wave Doppler, pulsed-wave tissue Doppler, and colour tissue Doppler imaging data will be obtained. All studies will be sent to a central echocardiographic core laboratory for quantitative analysis. Multiple studies will be performed for reproducibility analysis.
Conclusion
After completion of the NORRE Study, uniform reference limits according to age, gender, and anthropometric parameters will be available to standardize the quantitative interpretation of echocardiography.
Eur Heart J Cardiovasc Imaging first published online January 31, 2013
Background
Availability of normative reference values for cardiac chamber dimensions, volumes, mass, and function is a prerequisite for the accurate application of echocardiography for both clinical and research purposes. However, due to the lack of consistency in current echocardiographic ‘reference values’, their use for clinical decision-making remains questionable.
Aims
The aim of the ‘Normal Reference Ranges for Echocardiography Study (NORRE Study)’ is to obtain a set of ‘normal values’ for cardiac chamber geometry and function in a large cohort of healthy Caucasian individuals aged over a wide range of ages (25–75 years) using both conventional and advanced echocardiographic techniques.
Methods
The NORRE Study is a large prospective, observational multicentre study in which transthoracic echocardiographic studies will be acquired in 22 laboratories accredited by the European Association of Cardiovascular Imaging and in one laboratory in the USA accredited by ICAEL. The final sample size has been estimated in 1100 normal subjects in whom M-mode, 2D, and 3D imaging, colour Doppler, pulsed-wave Doppler, pulsed-wave tissue Doppler, and colour tissue Doppler imaging data will be obtained. All studies will be sent to a central echocardiographic core laboratory for quantitative analysis. Multiple studies will be performed for reproducibility analysis.
Conclusion
After completion of the NORRE Study, uniform reference limits according to age, gender, and anthropometric parameters will be available to standardize the quantitative interpretation of echocardiography.
Eur Heart J Cardiovasc Imaging first published online January 31, 2013
Пьянков Василий Алексеевич
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Мало собрать, надо еще опубликовать в известном журнале.sokolov166 писал(а):И? что тут эдакого? Мы свои детские нормативы (регрессии) вывели на анализе 2200 накопленных исследований подобного типа у здоровых детей, может быть повторим на 4000 еще раз.
Последний раз редактировалось AOkhotin Вт фев 26, 2013 6:05 pm, всего редактировалось 1 раз.
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Единственные настоящие Caucasians в данном исследовании представлены by the Echocardiography Laboratory of Adult Cardiology, Department of the JOANN Medical Center, Tbilisi, GA. И вовсе не Caucasians from SheikhKhalifa Medical City, Abu Dhabi, United Arab Emirates. В исследовании также принимают участие румынские и болгарские лаборатории. Российских нет?
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Не знаю есть ли в РФ эхокардиографические лаборатории аккредитованные European Association of Cardiovascular Imaging. Может быть только в Бакулевке у Мацкеплишвили?Igor Bulatov писал(а):Единственные настоящие Caucasians в данном исследовании представлены by the Echocardiography Laboratory of Adult Cardiology, Department of the JOANN Medical Center, Tbilisi, GA. И вовсе не Caucasians from SheikhKhalifa Medical City, Abu Dhabi, United Arab Emirates. В исследовании также принимают участие румынские и болгарские лаборатории. Российских нет?
Пьянков Василий Алексеевич
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- Сообщения: 5567
- Зарегистрирован: Пн ноя 24, 2008 12:59 am
- Откуда: Киров
Список EACVI аккредитованных Echo Lab.Pyankov Vasily писал(а):Не знаю есть ли в РФ эхокардиографические лаборатории аккредитованные European Association of Cardiovascular Imaging. Может быть только в Бакулевке у Мацкеплишвили?Igor Bulatov писал(а):Единственные настоящие Caucasians в данном исследовании представлены by the Echocardiography Laboratory of Adult Cardiology, Department of the JOANN Medical Center, Tbilisi, GA. И вовсе не Caucasians from SheikhKhalifa Medical City, Abu Dhabi, United Arab Emirates. В исследовании также принимают участие румынские и болгарские лаборатории. Российских нет?
http://www.escardio.org/communities/EAC ... ories.aspx
Российских лабораторий там нет.
Пьянков Василий Алексеевич